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Chronic administration of high doses of oral levocarnitine in patients with severely compromised renal function or in ESRD patients on dialysis may result in accumulation of the potentially toxic metabolites, trimethylamine (TMA) and trimethylamine-N-oxide (TMAO), since these metabolites are normally excreted in the urine

No peer-reviewed research confirms a causal relationship, though the mechanism warrants caution in individuals with oncological histories

Then the indenter gradually applied a load on the lens along the anteroposterior axis of the lens from above until 5.0 N (N) with the speed of 0.1 mm/s

J Nutr 133 , 41504157

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