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Preclinical and early-stage research literature has explored GHK-Cu in relation to oxidative stress response systems, inflammation-associated signaling pathways, and gene expression patterns linked to tissue maintenance

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Dikaios [152] used a database of 112 patients (81 GBM and 31 metastases) with both long-TE (using PRESS) and short-TE (using either STEAM and PRESS) MRS acquisitions from a nodular region where the biopsy was taken to create 31.500 synthetic spectra (six different datasets from two MR machines)