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10.7861/clinmedicine.13-1-7 82 QinB.XuY.ChenJ.HuangW.PengY.ZhengJ.et al (2016)

Medulloblastoma Paediatric brain tumour, believed to originate from primitive (undifferentiated) neuro-ectodermal cells, that most commonly arises in the cerebellum during the first decade of life and accounts for approximately 10% of primary brain tumours in children

N Engl J Med 383:452459 Monath TP, Nichols R, Archambault WT, Moore L, Marchesani R, Tian J, Shope RE, Thomas N, Schrader R, Furby D et al (2002) Comparative safety and immunogenicity of two yellow fever 17D vaccines (ARILVAX and YF-VAX) in a phase III multicenter, double-blind clinical trial

SH: Writing original draft, Writing review & editing

In this setting, HCY is elevated and an alternative, FAD-dependent channel is opened up across the methylation cycle to allow high, trapped levels of HCY to be metabolized