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Tempol, a membrane-permeable radical scavenger, attenuates peroxynitrite- and superoxide anion-enhanced carrageenan-induced paw edema and hyperalgesia: a key role for superoxide anion

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These solutions are chloride-free (or low chloride) to enable chloride shift (influx of the weak acid bicarbonate in exchange for the efflux of the strong chloride)

It could also induce megamitochondria, mitochondria pyknosis, tumidness and flocculent degeneration

The patient should be questioned closely about any symptoms from previous doses to prevent severe reactions