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L carnitine exerts a nutrigenomic effect via direct modulation of nuclear receptor signaling in adipocytes, hepatocytes and SKMC, demonstrating its nutritional impact ScienceDirect L carnitine, batch testing, and the problem with self prescription in elite sport. Oral L carnitine achieves bioavailability of just 1418% of the administered dose. In a well nourished elite athlete with no deficiency, the evidence for Frontiers Steroid Hormone Biosynthesis Metabolism Is Associated With Fatigue Related to Androgen Deprivation Therapy for Prostate Cancer Androgen receptor mutations modulate activation by 11 oxygenated androgens and glucocorticoids Prostate Cancer and Prostatic Diseases Inhibition of androgen receptor can decrease fat metabolism by decreasing carnitine palmitoyltransferase I levels in skeletal muscles of trained mice Nutrition & Metabolism Springer Nature Link
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