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Although it does not affect physical health, it can disrupt periorbital esthetics, revealing a tired and aged appearance, thereby affecting the patients quality of life (Citation13)

Guerrero JM, Reiter RJ (2002) Melatonin-immune system relationships

I have also included oral folate supplements, probiotics and have expanded my diet (but still excluding caffeine, alcohol and sugar)

Other groups of people who have a higher risk include people over age 60, people on certain medications for diabetes, people with Crohns disease, celiac, ulcerative colitis and irritable bowel syndrome and women with a history of infertility or miscarriage

In cancer, it is shown that membrane potential undergo hyperpolarization before entering M phase, and the levels are highly correlated with the sarcoma cell cycle progressions acting as an effective bioelectric regulator [160]