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Glutathione supplementation is most impactful for senior dogs (6+ years for large breeds, 8+ years for small breeds) because glutathione production naturally declines with age

A short flattening in a personal timeline is not automatically a signal to intervene it is often the expected shape of the response

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Keywords Methaqualone (Quaalude) Toxicology Source: a non-barbiturate sedative-hypnotic Mechanism of Action: a sedative hypnotic that stimulates the actions of GABA on GABA A receptors by binding to a transmembrane site distinctly different from the binding sites for benzodiazepines and barbiturates (Hammer et al, 2015) Symptoms: resembles barbiturate poisoning ataxia : produces pronounced motor problems & is known as wallbanger because of this phenomenon Can lead to severe muscular hypertonicity and seizures Treatment: no diuresis diazepam for severe muscular tone or seizures strongly consider phenytoin as an anticonvulsant because barbiturates potentiate the effect of methaqualone Notes: Methaqualone (quaaludes) were popular recreational drugs in the 1960's and 70's, especially in disco clubs

To this end, the use of oral vitamin B12 supplements such as vitamin B12 pills, capsules and drops has a limited effect