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doi: 10.3389/fimmu.2018.00090 43 DonTABethonyJMLoukasA

RT-PCR analyses for gene expression (Jyh-Chang Jean)

10,11 This compositional change affects host metabolism via the gutliver axis: conjugated bile acids act as antagonists of FXR in the intestine, inhibiting the intestinal FXR-FGF15/19 signaling pathway, leading to upregulation of hepatic cholesterol 7-hydroxylase expression and accelerating the conversion of cholesterol to bile acids, but may also promote hepatic lipogenesis

This is characterised by the potential cooling capacity of the identified green spaces using the proportion of shade, the ground surface and the absolute area size

Alrawaiq NS, Abdullah A