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For Type IV patients, we prefer mandelic acid at shallower depths, pre-treat with depigmenting agents when indicated, and apply more conservative timing during the procedure

96 A functional decline was observed in aging T and B cells

Although tbb-6 itself has a minor effect on the lifespan, knocking out its regulator, pmk-3 , attenuates the longevity phenotype of several mitochondrial mutants 35