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A 2025 systematic review in the American Journal of Sports Medicine confirmed preclinical support across tendon, ligament, muscle, and bone repair models while explicitly noting the absence of human clinical trial data (DOI: 10.1177/15563316251355551)

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WADA prohibits the administration of these substances when used to artificially raise levels beyond normal physiological ranges for the purpose of performance enhancement.

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Its now being investigated for potential longevity benefits and as a treatment for age-related macular degeneration

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