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The resulting construct was biolistically transformed into the gsh2 mutant background and positive transformants were selected on nourseothricin (100 g ml -1 )

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The reason these results are important is that niclosamide is currently being considered, formulated, and in some cases tested in clinical trials in a range of formulations, including a micronized niclosamide in spray dried lysozyme (37, 38, 77, 78)

DOI:10.1016/j.phymed.2015.10.015 75

To demonstrate this effect, CD3 + T cells were isolated from spleens of young and aged mice and treated with RSL3 ((1S,3 R)-RSL3), which induces ferroptosis by inhibition of glutathione peroxidase 4 (ref