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Although clinical symptoms should receive more weight in diagnosing B12 deficiency, the panelists recognized the need to use serum vitamin B12 concentrations as a cost-effective screening marker and the need to additionally measure a metabolic marker to support the diagnosis

While vitamin B12 supplements are considered safe and non-toxic, taking large doses of around 1,000 milligrams can still be problematic

Phase II Clinical Trials These promising preclinical findings led to Phase I and Phase II clinical trials in humans

Laser acupuncture can circulate blood for improving intracellular enzyme activity, regulate penetration of substance from vessel walls to reduce inflammation substance and repair damaged nerve, regulate immune system, and has anti-inflammatory and analgesic effect [19]