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and Hruby, V.J., Life Sci (1982) 31:189-199 (-CH -S-)' Peptide mimetics may have significant advantages over polypeptide embodiments, including, for example: more economical production, greater chemical stability, enhanced pharmacological properties (half-life, absorption, potency, efficacy, etc.), altered specificity (e.g., a broad-spectrum of biological activities), reduced antigenicity, and others

Randomized trial of Clazosentan in patients with aneurysmal subarachnoid hemorrhage undergoing endovascular coiling

[DOI] [PubMed] [Google Scholar] 114.Poblete-Aro C., Russell-Guzmn J., Parra P., Daz E., Reyes D., Saavedra M., Lanas F

At the same time, COXs are responsible for platelet aggregation, with inhibition leading to blood fluidification and a decrease in the occurrence of blood clots[1]

Taymans JM, Fell M, Greenamyre T, et al