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It may be particularly useful for adults who want to maintain strong immune defenses during seasonal changes, travel, or stressful periods

A 2010 meta-analysis indicated a significantly increased risk of new cancer occurrence in patients randomized to ARB therapy

Hirma S, Kiruma M, Lehmann K, Gopalan-Kriczky P, Qin GZ, Shinozuka H, Sato K, Lotlikar PD

Even more people have nutrient inadequacies---when intake of a nutrient is above the level usually associated with deficiency but below the estimated average requirement for healthy individuals---suggesting a potential for marginal deficiencies