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Understanding these variables is essential for practitioners who want to optimize treatment outcomes and educate patients properly

doi: 10.1097/CCM.0000000000004360 Andrews ET, Beattie RM, Tighe M

53,73 The disulfide bond reduction and irreparable trimming of N -linked glycans generate degrons selectively modified with glycans such as Man 7 GlcNAc 2 , Man 6 GlcNAc 2 , or Man 5 GlcNAc 2 , which prevents substrate re-engagement with calnexin or calreticulin for nonproductive folding cycles

Andreazza AC, Kapczinski F, Kauer-Sant'Anna M, Walz JC, Bond DJ, Goncalves CA et al

However, previous research in animal models of ASD has shown increased glutamate receptor binding during adolescence instead of childhood, potentially reflecting compensatory mechanisms for earlier synaptic alterations [60]