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Lu et al., 2018)

IGF-1 treatment increases IL-17 production by CD4 + T cells Given the increased expression of IGF-1R on Th17 cells, we next asked if IGF-1 would increase T cell production of IL-17 in vitro

Tesamorelin has the strongest clinical evidence for visceral fat reduction specifically, with FDA-approved data showing 15 to 20 percent reduction over 26 weeks