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[59] Clarkson TW, Magos L, Myers GJ

doi: 10.1016/s0168-1605(00)00456-6 226 KullisaarTZilmerMMikelsaarMVihalemmTAnnukHKairaneCet al

A recent meta-analysis of 13 RCTs revealed that vitamin C supplementation (a median dose of 500 mg/day for a median duration of 30 days) modestly reduced serum uric acid concentrations by -0.35 mg/dL compared to placebo (95% CI: -0.66, -0.03) (75)

Extracellular matrix (ECM) formation and cell migration are two complicated processes that must occur in order for inflammation to produce the atherosclerotic fibrous plaque