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Moving from personal responsibility to community leadership in a post-colonial developing world in Catalyzing Leadership Praxis in Developing Countries: History, Learning, and the New Community

10.1016/j.jcmgh.2016.12.002 37 FreyA

61 SIRT1 inhibits the activation of the NLRP3 inflammasome, which triggers the production of IL-1, IL-18, and HMGB1, therefore initiating and amplifying the innate immune response