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Cells have an enzymatic and non-enzymatic antioxidant defense system, but antioxidant molecules have been used to supplement culture media and thus decrease reactive oxygen species (ROS) production in gametes and embryos

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Therefore, it is clear that there is a need for global and/or regional regulatory procedures to control herbal medications [64]

Additionally, CTR1 gene expression is regulated by changes in specificity protein 1 (Sp1) activity and extracellular copper concentrations (28,29)