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It can spread to your lower back and legs

Tregs depend on FAO, utilizing lipid oxidation and OXPHOS for energy, which enables them to function in low-glucose conditions

This suggests that while IL-4 can activate 12/15-LOX, the IL-4 concentrations in the lungs of asthma patients may not be sufficiently high to induce significant ALOX15 expression

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Anyone with existing health conditions or on other medications should check with their doctor before starting