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These agents have demonstrated preclinical efficacy in reducing TMAO levels and mitigating cardiovascular risk, highlighting a potential avenue for precision microbiome-based therapy

However, they could be a possible alternative for men who cannot take certain medications or prefer a non-pharmaceutical approach

The Mayo Clinic indicates high doses of vitamin B-12, such as those used to treat a deficiency, might cause: Headache Nausea and vomiting Diarrhea Fatigue or weakness Tingling sensation in hands and feet Healthline says: In very rare cases, some people can experience side effects caused by allergic reactions or sensitivity In addition to helping athletes build muscle, vitamin B12 plays a role in maintaining nervous system function and brain health