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More importantly, a growing body of research reveals that these hepatoprotective effects do not stem from direct liver-targeted actions of TCM components but are achieved through an indirect pharmacological model: TCM acts as a 'modulator' to reshape the GM structure, which subsequently alters the profile and levels of microbiota-derived intermediary substances (e.g., metabolites such as SCFAs, BAs, TMAO, LPS, etc.)

Herrera & Ortega-Senovilla, 2017)

GRP, Gastrin-releasing peptide

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Legal Status of Hexarelin and Ipamorelin As far as the legal status is concerned, neither of them has yet been approved by the Food and Drug Administration for human consumption