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Neuropharmacology 2012

Wang J, Jia N, Zhu K, Xu K, Yan M, Lan M, et al

Recent findings have further supported these benefits, showing that oral nicotinamide administration provides robust, dose-dependent neuroprotection of RGCs in rat glaucoma models

In preclinical studies, compounds such as VX-765 and pralnacasan have demonstrated efficacy in inhibiting caspase-1 activation and protecting against inflammatory diseases