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The product should be formulated to minimize exposure to destabilizing agents, such as strong acids or excessive heat

Another phase 2 clinical study (NCT03325322) intends to evaluate the effects of oral fisetin on adipose tissue-derived mesenchymal stem/stromal cell function, kidney function, inflammation, and physical function in subjects with chronic kidney diseases and diabetes

human clinical trials are rare and preliminary

This represents approximately 3-fold improved local delivery and demonstrates that formulation significantly impacts outcomes

Side effects are uncommon and typically mild, such as temporary redness or irritation with topical use or slight discomfort at the injection site