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It exhibits a unique spiral morphology and thrives in extreme environmental conditions

FLSs, the dominant non-immune cells of the synovium, develop abnormal proliferative capacity and aggressive characteristics under oxidative stress conditions ( Figure 4 )

Hadadi E, Taylor W, Li X-M, Aslan Y, Villote M, Rivire J, Duvallet G, Auriau C, Dulong S, Raymond-Letron I, Provot S, Bennaceur-Griscelli A, Acloque H (2020) Chronic circadian disruption modulates breast cancer stemness and immune microenvironment to drive metastasis in mice

Conventional antihistamines work by blocking histamine receptors once histamine has been released

doi: 10.1016/j.intimp.2024.111940 Summary Keywords multi-omics, single-cell sequencing, glutathione metabolism, immunotherapy, prognostic model Citation Chi Y, Ma G, Liu Q, Xiang Y, Liu D and Du J (2025) Multi-omics analysis reveals glutathione metabolism-related immune suppression and constructs a prognostic model in lung adenocarcinoma