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Pregnant or breastfeeding women Individuals with a history of medullary thyroid carcinoma (MTC) Patients with multiple endocrine neoplasia type 2 (MEN2) Children and adolescents Those with significant GI motility disorders (unless cleared by a physician) Possible Side Effects of Cagrilintide Cagrilintide is generally well tolerated, but may cause: Nausea (dose-related) Decreased appetite Mild headache or fatigue GI side effects often resolve with slow dose titration

While adequate and well-controlled studies specifically in pregnant women are limited, vitamin B12 is essential, and its requirements increase during pregnancy

Because the mechanisms are entirely different and the active cycle windows are short, they can be scheduled sequentially under provider guidance without overlap

In women undergoing fertility treatments, a potentially life-threatening complication is ovarian hyperstimulation syndrome (OHSS), characterized by rapid weight gain, abdominal pain, ascites, and electrolyte imbalances

Together, they would target five distinct metabolic pathways simultaneously