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Mass Spectrometry Intact-mass analysis should support the molecular identity of reduced glutathione

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Abbreviations APX: ascorbate peroxidase AsA: ascorbate Cd: cadmium CAT: catalase DHA: dehydroascorbate DHAR: dehydroascorbate reductase Gly I: glyoxalase I Gly II: glyoxalase II GR: glutathione reductase GSH: reduced glutathione GSSG: oxidized glutathione H 2 O 2 : hydrogen peroxide H 2 S: hydrogen sulfide MDA: malondialdehyde MDHAR: monodehydroascorbate reductase MG: methylglyoxal MT: metallothionein NaHS: sodium hydrosulfide O 2 .- : superoxide radical PCS: phytochelatin synthase ROS: reactive oxygen species SOD: superoxide dismutase References Shah K, Kumar RG, Verma S, Dubey R

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Further investigation is needed to determine if TAM plays a role in this cell death pathway and if it could be harnessed for therapeutic benefit

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Mehrotra, D., Wu, J., Papangeli, I

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