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Glial dysfunction in the pathogenesis of alpha-synucleinopathies: emerging concepts

Combined with adequate protein intake (widely recommended at 1.2-1.6g per kg of body weight during GLP-1 protocols) and resistance training, the higher dose ranges may actually preserve lean mass better than lower doses, because the energy deficit is being met predominantly through fat oxidation rather than muscle catabolism

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Intrinsic factor deficiency leads to vitamin B12 deficiency, which can cause pernicious anemia, neurological symptoms, fatigue, and cognitive problems