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According to FDA prescribing information, you must also document two or more exacerbations within the past year despite high-dose inhaled corticosteroids plus additional controllers. Eligibility Checklist: Blood eosinophil count 150 cells/L confirmed by laboratory testing Age 6 years or older (specific dosing for pediatric patients) Two or more asthma exacerbations requiring systemic corticosteroids in past 12 months Currently using high-dose inhaled corticosteroids plus long-acting beta-agonist Documented severe asthma that remains uncontrolled despite optimal therapy Using our symptom checker before your appointment helps document attack frequency and patterns your doctor needs for prior authorization

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Acute and chronic asthma attacks can be managed by precisely identifying the regulators of these pathogenic pathways and targeting their molecular mediators