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Single-cell RNA-sequencing, metabolomic, proteomic, and transcriptomic analyses, together with immunoprecipitation, mass spectrometry, GST-pulldown assays, oxygen consumption rate assays, and other methods, were used to reveal the mechanism of PRMT1 in renal injury caused by CaOx crystals

tuberculosi s infection, in the corresponding group (Diet #1), consisted on 2.5 g CNCbl (Optovite B12, Normon laboratories) per week and per mouse, which translates the treatment prescribed for patients with B12 deficits into the animal model

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Controlled studies using validated appetite scales showed decreased hunger, increased satiety and reduced prospective food consumption scores with GLP-1 treatment, which translated into lower energy intake and weight reduction