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Mutant libraries reveal negative design shielding proteins from supramolecular self-assembly and relocalization in cells

In contrast, pharmacotherapy involves the application of pharmaceutical agents to combat cancer, focusing on maximizing drug effectiveness while curbing resistance (Zhang et al., 2024)

Furthermore, pinocembrin has been found to suppress oxidized low-density lipoprotein-activated NLRP3 inflammasome and GSDMD-facilitated endothelial cell pyroptosis via an Nrf2-dependent signaling pathway [176]