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Thus, the data from this study support the notion that BH4 can improve oxidative damage and methylation abnormalities in children with ASD with a large effect size, with the caveat that this effect may be more pronounced in those with the more severe abnormalities at baseline

KllikerFuse neurons send collateral projections to multiple hypoxia-activated and nonactivated structures in rat brainstem and spinal cord

When cells fail to neutralize free radicals, harmful cellular damage can occur and potentially affect many physiological processes

However, from basic mechanistic studies to translational applications, numerous critical challenges and unresolved questions remain

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