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First of all, the potential toxic and side effects of nanomaterials should be fully studied to ensure the safety of their application in clinical treatment

Materials and methods Animals and the development of ALF The investigation was conducted in accordance with the ethical treatment criteria for laboratory animals, as specified in the Guide for the Care and Use of Laboratory Animals and the ARRIVE recommendations

Endothelium-derived hyperpolarizing factor synthase (cytochrome P450 2C9) is a functionally significant source of reactive oxygen species in coronary arteries

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