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448,449 IMpassion130 also showed that atezolizumab plus nab-paclitaxel administered as first-line treatment produced significantly longer PFS in both the intention-to-treat population and the subgroup of patients with PD-L1-positive tumors

Precauciones y contraindicaciones de la carnitina La carnitina es un compuesto natural, por lo que es seguro

Vitamin C hydroxylates specific proline residues in hypoxia-inducible factor-I, which regulates hundreds of genes, and it also participates in the demethylation of DNA and histones and thereby influences the epigenome (26)

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Taken together, the combination of these natural compounds with chemotherapeutic drugs like 5-FU not only helps alleviate chemotherapy-induced gut dysbiosis and toxicity, but may also enhance the overall therapeutic efficacy by improving the intestinal microenvironment and reinforcing immunomodulatory and anti-inflammatory mechanisms