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However, standard oral glutathione supplements are often broken down by stomach acid before they can be absorbed

When acid reaches the throat, it can cause a burning sensation, commonly known as heartburn

In fact, it was the topic of one of my very first blogs

Therefore, we did not work experimentally with the variants reported in Table 2 or S4 , since all the predicted average changes for mutations in residues outside the core motif were mostly 1-2.5 kcal/mol ( Table S5 )