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Both SSU rDNA and RNA polymerase II data recognize that root knot nematodes arose from migratory Pratylenchidae, but probably not from one of the economically highimpact lesion nematodes

Participants were randomized 1:1:1 to retatrutide 9 mg weekly, retatrutide 12 mg weekly, or placebo, and treated for 68 weeks

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Tissue was collected from the angular gyrus of the parietal association cortex (Brodmann Area 39) due to the susceptibility of this region to A and tau neuropathology during intermediate Braak stages of AD, allowing separation of participants along a clinical spectrum 25,26