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It enhances the activity of the pyruvate dehydrogenase complex, promotes the conversion of pyruvate to acetyl CoA, and increases the TCA cycle efficiency by 20% -30%

The critical role of NAD + pool in tumorigenesis NAD + not only acts as a co-enzyme for metabolic redox reactions, but also functions as a co-substrate to modulate the activity of NAD + -consuming enzymes that govern the critical steps in tumorigenesis, including genome stability, metabolism, cell growth, cell death, redox homeostasis and immune response

Induction of intestinal Th17 cells by segmented filamentous bacteria

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