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A more likely reason for deficiency would be low absorption in the gut, probably because of pernicious anemia or another condition

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Ipamorelin stands out as more selective compared to other member compounds of the GHS class, as it stimulates growth hormone release without affecting the synthesis of other pituitary hormones, such as ACTH or prolactin [12]

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This paper shows that the receptor TOM70 of the mitochondrial outer membrane interacts with inositol trisphosphate receptors of the ER, supporting the formation of contact sites for Ca 2+ transfer to mitochondria