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KovcsRRabanusAOthalJPatzakAKardosJAlbusKet al

10.1161/CIR.0000000000000912 24

As one of the most important dopamine-replacement therapies for PD, L-DOPA is commonly given with carbidopa to improve bioavailability and avoid early conversion into dopamine before penetration into the brain (Gandhi and Saadabadi, 2025)