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10.1128/msystems.00273-22 mSystems

The compound is notoriously unstable once mixed with water: reduced glutathione (GSH) oxidises to glutathione disulfide (GSSG) within hours at room temperature, stripping the molecule of its electron-donating capacity and rendering it therapeutically inert

There is consensus that chronic inflammation is a significant contributor to a wide range of diseases such as cardiovascular and autoimmune diseases, diabetes, arthritis, cystic fibrosis, Alzheimers disease, autism, Parkinsons diseases, mild cognitive impairment and even tumors

Keywords: melanin index, melanogenesis, oxidized glutathione, reduced glutathione, skin whitening, topical Introduction Skin aging is a complex biological phenomenon consisting of two independent clinically and biologically distinct processes, namely intrinsic aging and extrinsic aging. 1,2 Extrinsic aging (including photoaging) is the result of exposure to outdoor elements, primarily ultraviolet (UV) irradiation