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IGF-1 is the primary anabolic mediator it promotes protein synthesis, collagen production, bone mineralization, and cellular regeneration

Immediate side effects from mesotherapy treatment may include redness, pricking, stinging and a burning sensation, lasting up to two to three hours at the injection sites

Cold solutions are slightly more viscous, which can make drawing slower and less accurate

These medications include proton pump inhibitors (which are sometimes prescribed for people with GERD), the gout medication colchicine, the diabetes drug metformin, and H2 blockers such as Pepcid

In preclinical research models, it has been studied extensively for its involvement in angiogenesis (new blood vessel formation), fibroblast activity and collagen synthesis, growth factor modulation (including VEGF and EGF pathways), connective tissue signaling in muscle, tendon, and ligament models, gastrointestinal mucosal integrity, and inflammatory cytokine modulation