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Targeting phenylpyruvate restrains excessive NLRP3 inflammasome activation and pathological inflammation in diabetic wound healing

In line with what was previously mentioned, several studies point out the rich content in bioactive compounds like dietary fibresand polyphenols in food byproducts like apple, berry pomace, or potato, passion fruit, and orange peels (Table 2)

Fe 2+ aggregates exhibited high phototoxicity (808 nm, 0.4 W cm 2 , 10 min), with a 90 M dose of Fe 2+ aggregates resulting in the death of over 80% of 4T1 cells, whereas Mn 2+ aggregates and free dye only caused approximately 70% and 20% cell death, respectively

Hassoba H, El-Sakka A, Lue T

The regulation of INK4/ARF in cancer and aging, Cell