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Research has shown that individuals with depression, particularly those experiencing recurrent episodes, exhibit significantly elevated levels of 8-OHdG compared to normal levels (Omari Shekaftik and Nasirzadeh, 2021

[Updated 2021 Feb 9]

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However, there are specific circumstances when patients should seek medical advice regarding B12 levels and related concerns

It is possible that some people who develop symptoms of a vitamin B12 deficiency with no clear causative factors may have antibody-negative pernicious anaemia[2]