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Dihydrotanshinone, Tanshinone IIA, and cryptotanshinone are three constituents of tanshinone that partially counteract chemoresistance in CRC

It aids in melanin formation which then yields an effect of a lipoic acid on B16 melanoma

The primary mechanisms suggested include: Bile Flow Stimulation : The caffeine in coffee may enhance the production and flow of bile from the liver, facilitating the elimination of toxins

Cantaert et al

But it's important to note that dietary glutathione through specific foods is not easily available due to digestive enzymes breaking it down into amino acids