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[DOI] [PubMed] [Google Scholar] 38.Deterding K, Grngreiff K, Lankisch TO, Potthoff A, Bahr MJ, Manns MP, Wedemeyer H, Strassburg CP

Heat can denature proteins and reduce the potency of the antioxidants

Depending on the type of stress encountered, specific ISR kinases (PKR, HRI, GCN2, and PERK) are activated that phosphorylate the eukaryotic translation initiation factor 2 subunit alpha (eIF2) (113)