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10.1093/oxfordjournals.aje.a009122 52

Sharp's team is currently studying whether the siRNAs can promote nerve regeneration after spinal cord injuries

Science 279, 17181722

TPP, the biologically active form of thiamine (vitamin B 1 ), is tightly bound to the enzyme and participates in the transfer of activated aldehyde intermediates by stabilizing the two-carbon carbanions formed during the reaction