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Based on a validated observers rating scale, they were divided into Good (n = 15) and Mild (n = 23) responders, and the two groups were compared from various clinical aspects

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The tumor regrowth rechallenge performed after day 94 of the study confirmed that F-LALA-VA-EXA is able to induce a protective immunologic memory response, as no tumor growth was observed after re-implantation of the groupe treated with F-LALA-VA-EXA at 12mg/kg IV once (a positive control group with new untreated SCID mice showed tumor growth after implantation)

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318 SahmA.PlatzerM.KochP.HenningY.BensM.GrothM.et al (2021)

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This conservative protocol prioritizes long-term safety while still achieving meaningful telomerase activation

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