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Certain phytoestrogens, such as the flavonoid genistein, can promote glucose uptake and metabolism [3] by activating the GPER-mediated cAMP/PKA-AMPK signaling pathway and increasing the expression of glucose transporter glucose transport protein 2 (GLUT2)

Hum Reprod (1999) 14(2):3548

Lancet 1 , 643647 (1982)

It is recommended to introduce external synthetic spike-in controls or use biologically significant ratio indicators in the detection system to eliminate systematic errors, thereby ensuring the robustness and cross-center comparability of diagnostic results (145)

Increased IL-1 levels elevate iron regulatory protein 1 and TFR1 in oligodendrocytes, while reduced iron transporter protein 1 expression leads to intracellular iron accumulation, contributing to neurodegenerative diseases (Yang J