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The approval is backed by data from Part 1 of the Phase III RUBY trial, where treatment with the Jemperli regimen led to a 31% reduction in risk of death compared to chemotherapy alone

For references and more information , see the section on Cardiovascular disease in the Folate article

Third, large volume MRS VOIs were used in this study due to the low GSH levels and resonances of GSH overlapping with other metabolites

2015;51C:1007

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