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This ratio reflects the activity of lecithin cholesterol acyl transferase (LCAT, EC 2.3.1.43), an enzyme bound to HDL-C particles [52, 53]

The volume of MNP-GDH CL was kept the same as the purified Bs GDH immobilization to be able to make a direct comparison to the purified enzyme

doi:10.1155/2013/928290 42

This is particularly important in the brain, where elevated iron levels can lead to the production of ROS, contributing to neuronal damage and neurodegeneration (256,257)